Focal fits during chlorambucil therapy

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Focal fits during chlorambucil therapy.

Introduction Chronic lymphatic leukaemia is a disease of the elderly with a long natural history. Treatment is palliative, with chlorambucil the drug of choice (Livingston and Carter, 1970). The recognized side effects of chlorambucil include nausea, myelosuppression, skin eruptions and pulmonary fibrosis (Stenfert Kroese, 1975), but their incidence is low. Although high doses of chlorambucil a...

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C (CHL) had been used as treatment for childhood nephrotic syndrome (NS) for more than half a century.1 It was used mainly in children with steroid sensitive nephrotic syndrome (SSNS) as steroid sparing agent in those with frequent relapsing or steroid dependent course.2 However, it was observed to result in higher rates of severe side effects and recommended as a second line drug after cycloph...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1979

ISSN: 0032-5473

DOI: 10.1136/pgmj.55.649.806